Infectious Diseases

The University of Notre Dame has long been recognized for its contributions to infectious disease research, particularly in vector-borne diseases, such as malaria and dengue. Other important areas of research include tuberculosis, antimicrobial resistance, and neglected tropical diseases, such as leishmaniasis and schistosomiasis.

Building on Notre Dame’s pioneering work in biological sciences and infectious diseases by George B. Craig Jr., and Frank Collins, the founding director of the precursor organization that became the Eck Institute for Global Health in 2010, the Institute continues to lead in the prevention, detection, and treatment of infectious diseases that remain among the leading causes of illness and death worldwide.

Today, the Eck Institute brings together experts from across disciplines, spanning biology, chemistry, the social sciences, engineering, business, and economics. This collaborative approach drives solutions to infectious disease threats, from mosquito-borne diseases and tuberculosis to antimicrobial resistance.

Our integrated perspective transforms research into real-world solutions that save lives and shape global health policy.

Infectious Diseases and Environmental Factors

Over the years, our affiliated and core researchers have led extensive studies on malaria, dengue, and tuberculosis, diseases that profoundly affect communities and shape health systems across diverse cultural contexts worldwide.

The Eck Institute recognizes the inextricable link between environmental factors and infectious diseases. Our research examines how air and water quality, pollution, vector habitats, and climate change influence the spread and severity of infectious diseases. By identifying and mitigating environmental drivers, we work toward sustainable, science-based solutions that protect both ecosystems and human health.

Tackling Antimicrobial Resistance and Emerging Threats

As antimicrobial resistance continues to rise globally, Notre Dame investigators are advancing research to safeguard the effectiveness of life-saving treatments. Our efforts span the development of new diagnostics, drugs, and vaccines, the strategic repurposing of existing therapies, and the strengthening of surveillance systems to track resistance patterns.

Through a focus on both innovation and global stewardship, we contribute to more informed treatment strategies and help ensure that effective antimicrobials remain available for generations to come.

Building Resilient Systems, Reducing Disparities

Infectious diseases disproportionately impact communities with limited access to preventive care and health infrastructure. The Eck Institute’s commitment to closing these gaps means partnering with stakeholders around the world to build capacity, strengthen surveillance systems, and ensure timely access to care and treatment.

By bringing together expertise from academia and a wide range of public and private partners, Notre Dame is not only confronting today’s infectious disease challenges but also laying the groundwork for healthier, more resilient communities in the years to come.