African Center for hrp2/3 Deletion Surveillance (ACHIDES)
The majority of rapid diagnostic tests for the diagnosis of P. falciparum malaria detect the HRP2 protein. Deletions of the hrp2 gene result in false-negative tests. Molecular monitoring of hrp2 deletions is a high-priority task of the WHO. We established a molecular lab in Ethiopia and apply an innovative new method for deletion screening across Ethiopia and beyond.
At the EIGH, our researchers use epidemiology to understand the distribution and determinants of the health and disease conditions in specific populations, and to identify risk factors for certain diseases. This allows them to develop, implement, and measure the impact of targeted, preventative healthcare methods.
Genetics and Genomics
One way to study certain diseases is through genetics - the study of heredity and the variation of individual inherited genes in an organism. At the EIGH, this means studying how organisms can inherit and spread certain diseases. Additionally, by analyzing the entire structure, function, and evolution of an organism's genes, researchers may identify ways to prevent a disease from genetically passing disease traits.
At the EIGH, our researchers work to combat a number of various illnesses, including infectious diseases caused by organisms like bacteria, viruses, fungi, and parasites. These diseases can also be spread from one person to another and may be transmitted from animals to humans.
- Armauer Hansen Research Institute (AHRI), Addis Ababa, Ethiopia