FACULTY SPOTLIGHT:

Malcolm Fraser:

Working to eradicate dengue fever.

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Active Projects Associated with the Institute

NORA BESANSKY
Ecological Genomics of Anopheles gambiae

FRANK COLLINS
Malaria Transmission Consortium
VectorBase: A Bioinformatics Resource Center for Invertebrate Vectors of Human Pathogens

MICHAEL FERDIG
Copy Number Variation in Malaria Parasites
Determinants of Growth and Fitness in Drug Resistant Malaria Parasites
Genetic Control of Cross-Resistance in Plasmodium Falciparum
High-resolution Hybridization-based Genotyping in Plasmodium Falciparum

MALCOLM FRASER
• A Novel Transgenic Silkworm System for Recombinant Glycoprotein Production
• Developing Coupled Transgenic Ribozyme and Insecticide Resistance Approaches to Establishing
Dengue Virus Refractoriness in Natural Populations
• Engineering Transgenic Silkworms to Product Synthetic Spider Silk Fibers
• Transgenic Engineering of Aedine Mosquitoes Using the PiggyBac Transposon

HOPE HOLLOCHER
The Impact of Population Structure on Pathogen Transmission in Balinese Macaques

MARY ANN MCDOWELL
• Inhibition of Interleukin-12 in Leishmania-infected Macrophages
Interleukin-12 Regulation in Leishmania-infected Human Dendritic Cells
Sand Fly Genome Project and Anti-Saliva Vaccine Development

JEANNE ROMERO-SEVERSON
The Indiana Center for Insect Genomics

JEFF SCHOREY
M. Avium Gpls in Macrophage Activation and Virulence
• Macrophage Signaling Upon M. Avium Infection

DAVID SEVERSON
Molecular Genetics of Dengue Resistance in Mosquitoes

TOM STREIT, CSC
• Eliminating Lymphatic Filariasis in Haiti
• Asante Foundation Grant in Support of the Haiti Project

Other Faculty Research Projects

GARY BELOVSKY
• LTREB: Ecosystem Structure and Function in Palouse Grasslands
• Luquillo LTER Program 4: Understanding Change in the Ecosystems of Northeastern Puerto Rico
• Contract to Conduct Laboratory and in situ Experiments on Brine Shrimp
• Dissertation Research: Community Level Response to Global Change: The Effect of Temperature on the
Relative Importance of Top-down and Bottom-up Effect

MOLLY DUMAN SCHEEL
Analysis of axon guidance gene function during vector mosquito development

JEFFREY FEDER
• Genomics of Diapause and Chemoreception in the Apple Maggot Fly
• IGERT: Global Linkage of Biology, Environment, and Society (GLOBES)
• Collaborative Research: Diapause Energetics in the Apple Maggot Rhagoletis Pormonella
• The Biogeography of Sympatric Speciation in Rhagoletis
• Collaborative Research: Host Race Formation among Southern Hawthorn-Infesting Rhagoletis pomonella

JESSICA HELLMANN
• Collaborative Research: Interdisciplinary Workshop on Assisted Migration
• Predicting the Impact of Climate Change on Animal Distributions: The Importance of Local Adaptation and Species Traits
• Genomic Research on Terrestrial Insects and Aquatic Microorganisms as Indicators of Global Change
• Assisted migration: evaluating a new strategy for species' conservation

HOPE HOLLOCHER
Leakey Foundation. Balinese macaques: A model of human evolution in a pathogenic environment
• Dissertation Improvement Grant: Examination of Expression Profile Differences in Candidate Loci
Underlying Female Hybrid Sterility in Drosophila

DAVID LODGE
• Developing and Applying a Real-time Generic Probe for Detecting Aquatic Invasive Species in Ships’
Ballast
• Aquatic Invasive Species Research: Economic Impact of Ballast Water-Mediate Invasive Species
• Ecological Forecasting
• Risk Assessment and Management of Great Lakes Invasive Species

SHAHRIAR MOBASHERY
• Resistance to β-Lactam Antibiotics
• Penicillin-Binding Proteins, Mechanism and Inhibition
• Intervention of Disease by Selective Gelatinase Inhibitors
• Bacterial Cell Wall and Its Turnover
• Targeting MT-MMPs in Cancer Progression

 
 
   
     

Contact Information: Telephone: 574-631-2171
Fax: 574-631-3996; e-mail: eigh@nd.edu
Department of Biological Sciences
University of Notre Dame
Notre Dame, Indiana 46556