Introduction to Systems Biology
Number of Credits:
The goal of this course is to highlight elementary design principles inherent in biology. Many of the underlying principles governing biochemical reactions in a living cell can be related to network circuit motifs with multiple inputs/outputs, feedback and feedforward. This course draws on control theory and elementary biology to provide a mathematical framework to understand biological networks. The topics examined in the course are drawn from current research and include: transcription networks, stochastic gene induction, adaptation, oscillators (circadian rhythms), riboswitches, plasticity, metabolism, pattern development and cancer. The course is intended for advanced undergraduates and graduate students. There is an optional lab that focuses on transforming bacteria, stem cell biology and stochastic simulation.